One theory I like is: Gut-Brain connection. Gut composition signals to brain.

If a child took antibiotics the gut loses its balances, this has to be rebuild with the right food.

If this dysbalance stays long enough it can affect the development of the brain. I’m not saying it’s damage mkay.

What supports this hypothesis is that gut-brain mechanism is insanely underexplored.

(English 2nd etc)

Misguided, irrational, batshit, ridiculous, offensive, mind-bogglingly stupid, there are a lot of words one might use.

Fuckin stupid and a waste of my tax dollars is what I call it.

Anyone with half a brain can see that. I guess the worm left slightly less than half.

God he looks like a monster wearing a mansuit. Absolutely ghoulish inside and out.

Experts need to stop being nice.

Everyone knows he already has what he’s going to market as the “cause,” and it’s vaccines. Which he’ll spend another three years telling the country that it’s better that their children die in adolescence of a completely preventable disease than risk becoming autistic, no matter how many times that supposed link is disproven, siphoning resources away from our autistic kids that are doing well, even thriving, with the assistance and accomodations they’re now at risk of losing.

It’s not “unrealistic.” It’s fucking moronic and malicious. At best, this whole thing is part of some overall eugenics scheme to justify this administration’s genocide goal. Call this shit out.

I wish he wasn’t such a dumbass because it’s a real phenomenon that needs investigated.

Most likely IMO is RCCX Theory.

The RCCX module is a complex, highly variable gene cluster on chromosome 6 within the Major Histocompatibility Complex (MHC), a region crucial for immune function and hormone regulation. It includes genes like C4 (complement component 4), CYP21A2 (21-hydroxylase), TNXB (tenascin-X), and pseudogenes.

Hypothesized Mechanisms Linking RCCX to Autism

1.

Hormonal Dysregulation (Prenatal Androgen Exposure)

• The CYP21A2 gene encodes 21-hydroxylase, critical in cortisol and aldosterone synthesis.
• Mutations or variations can lead to Congenital Adrenal Hyperplasia (CAH) or milder forms of hormonal imbalance.
• This results in elevated prenatal androgen exposure, linked to autistic traits via the “Extreme Male Brain” theory proposed by Simon Baron-Cohen.

2.

Immune System Dysregulation

• The C4 gene is vital for the complement cascade, involved in synaptic pruning during brain development.
• Variants leading to C4 overexpression or underexpression could disrupt normal synapse elimination, contributing to aberrant neural connectivity, a hallmark of autism.

3.

Structural and Connective Tissue Abnormalities

• The TNXB gene affects connective tissue integrity.
• Variants are associated with Ehlers-Danlos Syndrome (hypermobility type), which has a comorbidity with autism.
• Connective tissue dysfunction could contribute to sensory processing issues often seen in autistic individuals.

4.

Genetic Instability and Copy Number Variations (CNVs)

• The RCCX module is prone to unequal crossover events during meiosis, leading to CNVs.
• These CNVs can disrupt gene dosage balance for C4, CYP21A2, and TNXB, increasing susceptibility to neurodevelopmental disorders.

5.

Stress Axis Dysregulation (HPA Axis)

• Disruption in cortisol production affects the Hypothalamic-Pituitary-Adrenal (HPA) axis, altering the stress response.
• Early-life dysregulated stress responses are frequently observed in autistic children.

Summary Table

Find autism’s cause and give it to everyone.