I recently moved Nextcloud and Gitea from Containers on a Debian VM to Alpine LXCs running Alpine’s packages. I’ve never had Nextcloud’s web interface so snappy and my resource usage for both is next to 0. If you’re running Proxmox I’d highly recommend trying out Alpine LXCs if they package your services.
I’ve played with both Alpine and Debian in LXC, launched multiple services in both at the same time, and, honestly, did not notice any advantages in RAM or CPU consumption. Debian LXC uses slightly more disk, but this is trivial for me
Alpine packages services like Gitea and Nextcloud which Debian does not. This makes keeping up to date alot simpler for myself but that’s personal preference.